• Inhibition of the Clostridioides difficile Class D β‐Lactamase CDD‐1 by Avibactam. Stewart NK, Toth M, Stasyuk A, Lee M, Smith CA, Vakulenko SB, ACS Infect. Dis. 2021, ASAP.

  • The Selective MMP-9 Inhibitor (R)-ND-336 Alone or in Combination with Linezolid Accelerates Wound Healing in Infected Diabetic Mice. Peng Z, Nguyen TT, Song W, Anderson B, Wolter WR, Schroeder VA, Hesek D, Lee M, Mobashery S, Chang M, ACS Pharmacol. Trans. Sci. 2021, ASAP.

  • Minimal deuterium isotope effects in quantitation of dimethyl-labeled complex proteomes analyzed with capillary zone electrophoresis/mass spectrometry. Yan X, Sun L, Dovichi NJ, Champion MM,  Electrophoresis 2020, 41, 1374.

  • Quantitative capillary zone electrophoresis-mass spectrometry reveals the N-glycome developmental plan during vertebrate embryogenesis. Qu Y, Dubiak KM, Peuchen EH, Champion MM, Zhang Z, Hebert AS, Wright S, Coon JJ, Huber PW, Dovichi NJ. Mol. Omics 2020, 16, 210.

  • EspM Is a Conserved Transcription Factor That Regulates Gene Expression in Response to the ESX-1 System. Sanchez KG, Ferrell MJ, Chirakos AE, Nicholson KR, Abramovitch RB, Champion MM, Champion PA. mBio 2020, 11, e02807-19.

  • Structural insights into peptidoglycan reshaping by a noncanonical peptidase for helical cell shape in intestinal pathogens. Min K, An DR, Yoon H-J, Rana N, Park JS, Lee M, Hesek D, Kim BM, Mobashery S, Suh SW, Lee HH, Nat. Commun. 2020, 11, 458.

  • The Streptococcal Protease SpeB Antagonizes the Biofilms of the Human Pathogen Staphylococcus aureus USA300 through Cleavage of the Staphylococcal SdrC Protein. Carothers KE, Liang Z, Mayfield J, Donahue DL, Lee M, Boggess B, Ploplis VA, Castellino FJ, Lee SW, J. Bacteriol. 2020, 202, e00008-20.

  • Transforming growth factor B (TGF-β) receptor signaling regulates kinase networks and phosphatidyl-inositol metabolism during T-cell activation. Cattley RT, Lee M, Boggess WC, Hawse W, J. Biol. Chem. 2020, 295, 8236.

  • Developing a mass spectrometry-based assay for the ovarian cancer biomarker CA125 (MUC16) using suspension trapping (STrap). Schuster-Little N, Madera S, Whelan R, Anal. Bioanal. Chem. 2020, 412, 6361. 

  • Miniaturized Filter-Aided Sample Preparation (MICRO-FASP) Method for High Throughput, Ultrasensitive Proteomics Sample Preparation Reveals Proteome Asymmetry in Xenopus laevis Embryos. Zhang Z, Dubiak KM, Huber PW, Dovichi NJ, Anal. Chem. 2020, 92, 5554.

  • Methylisatin Structural Isomers Have Different Kinetic Pathways to Self-Assembly. Silski-Devlin AM, Petersen JP, Liu J, Corcelli SA, Kandel SA, J. Phys. Chem. C 2020, 124, 17717.

  • Membrane-Based Affinity Purification to Identify Target Proteins of a Small-Molecule Drug. Yang L, Bui L, Hanjaya-Putra D, Bruening ML, Anal. Chem. 2020, 92, 11912.

  • Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division. Alcorlo M, Dik DA, De Benedetti S, Mahasenan KV, Lee M, Dominguez-Gil T, Hesek D, Lastochkin E, Lopez D, Boggess B, Mobashery S, Hermoso JA, Nat. Commun. 2019, 10, 5567.

  • A New ESX-1 Substrate in Mycobacterium marinum That Is Required for Hemolysis but Not Host Cell Lysis. Bosserman RE, Nicholson KR, Champion MM, Champion PA, J. Bacteriol. 2019, 201, e00760.

  • Capillary Zone Electrophoresis with Fraction Collection for Separation, Culturing, and Identification of Bacteria from an Environmental Microbiome. Huge BJ, Champion MM, Dovichi NJ, Anal. Chem. 2019, 91, 4649.

  • Single-Shot Capillary Zone Electrophoresis–Tandem Mass Spectrometry Produces over 4400 Phosphopeptide Identifications from a 220 ng Sample. Zhang Z, Hebert AS, Westphall MS, Coon JJ, Dovichi NJ, J. Proteome Res. 2019, 18, 3166.

  • Variations in the Secondary Structures of PAM Proteins Influence their Binding Affinities to Human Plasminogen. Qiu C, Yuan Y, Zajicek J, Liang Z, Lee SW, Ploplis VA, Castellino FJ, J. Struct. Biol. 2019, 206, 2, 193.

  • SIt, MltD, and MltG of Pseudomonas aeruginosa as Targets of Bulgecin A in Potentiation of β-Lactam Antibiotics. Dik DA, Madukoma CS, Tomoshige S, Kim C, Lastochkin E, Boggess WC, Fisher JF, Shrout JD, Mobashery S, ACS Chem. Biol. 2019, 14, 296.
  • A Synthetic Dual Drug Sideromycin Induces Gram-Negative Bacteria To Commit Suicide with a Gram-Positive Antibiotic. Liu R, Miller PA, Vakulenko SB, Stewart NK, Boggess WC and Miller MJ, J. Med. Chem. 2018, 61, 3845.
  • Enzyme-Containing Spin Membranes for Rapid Digestion and Characterization of Single Proteins. Liu W, Pang Y, Tan H, Patel N, Jokhadze G, Guthals A and Bruening ML, Analyst 2018, 143, 3907.
  • Site-Specific Glycan Heterogeneity Characterization by Hydrophilic Interaction Liquid Chromatography Solid-Phase Extraction, Reversed-Phase Liquid Chromatography Fractionation, and Capillary Zone Electrophoresis-Electrospray Ionization-Tandem Mass Spectrometry. Qu Y, Sun L, Zhang Z and Dovichi NJ, Anal. Chem. 2018, 90, 1223.
  • Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development. Peuchen EH, Cox OF, Sun L, Hebert AS, Coon JJ, Champion MM, Dovichi NJ, Huber PW, Sci. Rep. 2018, 8, 17393.
  • Myeloid-derived suppressor cells inhibit T cell activation through nitrating LCK in mouse cancers. Feng S, Cheng X, Zhang L, Lu X, Chaudhary S, Teng R, Frederickson C, Champion MM, Zhao R, Cheng L, Gong Y, Deng H, Lu X, Proc. Natl. Acad. Sci. U.S.A. 2018, 115, 10094.
  • Quantitative N-Terminal Footprinting of Pathogenic Mycobacteria Reveals Differential Protein Acetylation. Thompson CR, Champion MM, Champion PA, J. Proteome Res. 2018, 17, 3246.
  • Ultrahigh-Purity Vanadyl Petroporphyrins. Rytting B, Singh I, Kilpatrick P, Harper M, Mennito A, Zhang Y, Energy & Fuels, 2018, 32, 5711.
  • A Synthetic Dual Drug Sideromycin Induces Gram-Negative Bacteria To Commit Suicide with a Gram-Positive Antibiotic. Liu R, Miller PA, Vakulenko SB, Stewart NK, Boggess WC and Miller MJ, J. Med. Chem. 2018, 61, 3845.
  • MALDI Mass Spectrometry Imaging for Evaluation of Therapeutics in Colorectal Tumor Organoids. Liu X, Flinders C, Mumenthaler SM and Hummon AB, J. Am. Soc. Mass Spectrom. 2018, 29, 516.
  • Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa. Lee M, Batuecas MT, Tomoshige S, Domínguez-Gil T, Mahasenan KV, Dik DA, Hesek D, Millán C, Usón I, Lastochkin E, Hermoso JA, Mobashery S, Proc. Natl. Acad. Sci. U.S.A. 2018, 115, 4393.
  • (R)-ND-336 as a Therapeutic Agent for Diabetic Wound Healing. Nguyen TT, Ding D, Wolter WR, Perez R, Champion MM, Mahasenan KV, Hesek D, Lee M, Schroeder VA, Lastochkin E, Rose MK, Peterson CE, Suckow MA, Mobashery S, Chang M, J. Med. Chem. 2018, 61, 8825.
  • WhiB6 Regulation of ESX-1 Gene Expression is Controlled by a Negative Feedback Loop in Mycobacterium marinum. Bosserman RE, Nguyen TT, Sanchez KG, Chirakos AE, Ferrell MJ, Thompson CR, Champion MM, Abramovitch RB and Champion PA, Proc. Natl. Acad. Sci. U.S.A. 2017, 114, E10772.
  • From Genome to Proteome to Elucidation of Reactions for All Eleven Known Lytic Transglycosylases from Pseudomonas aeruginosa. Lee M, Hesek D, Dik AD, Fishovitz J, Lastochkin E, Boggess B, Fisher JF, Mobashery S, Angew. Chem., Int. Ed. 2017, 56, 2735.
  • Deciphering the Nature of Enzymatic Modifications of Bacterial Cell Wall. Lee M, Hesek D, Lastochkin E, David AD, Boggess B, Mobashery S, ChemBioChem 2017, 18, 1696.
  • Muropeptide binding and the X-ray structure of the effector domain of the transcriptional regulator AmpR of Pseudomonas aeruginosa. Dik DA, Domínguez-Gil T, Lee M, Hesek D, Byun B, Fishovitz J, Boggess B, Hellman LM, Fisher JF, Hermoso JA, Mobashery S, J. Am. Chem. Soc. 2017, 139, 1448.
  • Muropeptides in Pseudomonas aeruginosa and their Role as Elicitors of β-Lactam-Antibiotic Resistance. Lee M, S Dhar, De Benedetti S, Hesek D, Boggess B, Blázquez B, Mathee K, Mobashery S. Angew. Chem., Int. Ed. 2016, 55, 6882.
  • Single Cell Proteomics Using Frog (Xenopus laevis) Blastomeres Isolated from Early Stage Embryos, Which Form a Geometric Progression in Protein Content. Sun L, Dubiak KM, Peuchen EH, Zhang Z, Zhu G, Huber PW, Dovichi NJ, Anal. Chem. 2016, 88, 13, 6653.
  • Capillary zone electrophoresis for bottom-up analysis of complex proteomes. Sun LL, Zhu GJ, Yan XJ, Zhang ZB, Wojcik R, Champion MM, Dovichi NJ. Proteomics, 2016, 188.
  • Catalytic Spectrum of the Penicillin-Binding Protein 4 of Pseudomonas aeruginosa, a Nexus for the Induction of β-Lactam Antibiotic Resistance. Lee M, Hesek D, Blázquez B, Lastochkin E, Boggess B, Fisher JF, Mobashery S. J. Am. Chem. Soc. 2015, 137, 190.
  • Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury. Lee M, Chen Z, Tomlinson BN, Gooyit M, Hesek D, Juarez MR, Nizam R, Boggess B, Lastochkin E, Schroeder VA, Wolter WR, Suckow MA, Cui J, Mobashery S, Gu Z, Chang M, ACS Chem. Neurosci. 2015, 6, 1658.
  • Incorporating yeast biosensors into paper-based analytical tools for pharmaceutical analysis. Weaver AA, Halweg S, Joyce M, Lieberman M, Goodson HV, Anal. Bioanal. Chem. 2015, 615.
  • Mass Spectrometry Imaging of Therapeutics from Animal Models to Three-Dimensional Cell Cultures. Liu X, Hummon AB, Anal. Chem. 2015, 9508.
  • Chemometric analysis of MALDI mass spectrometric images of three-dimensional cell culture systems Weaver EM, Hummon AB, Keithley RB, Anal. Methods 2015, 7208.
  • A Comparison of Alternating Current and Direct Current Electrospray Ionization for Mass Spectrometry. Sarver SA, Chetwani N, Dovichi NJ, Go DB, Gartner CA, J. Am. Soc. Mass Spectrom. 2014, 524.
  • A Chemical Biological Strategy to Facilitate Diabetic Wound Healing. Gooyit MM, Peng Z, Wolter WR, Pi H, Ding D, Hesek D, Lee M, Boggess B, Champion MM, Suckow MA, Mobashery S, Chang M, ACS Chem. Biol. 2014, 9, 105.
  • Daily rhythms in antennal protein and olfactory sensitivity in the malaria mosquito Anopheles gambiae Rund SS, Bonar NA, Champion MM, Ghazi JP, Houk CM, Leming MT, Syed Z, Duffield GE, Sci Rep, 2013, 3, 2494.
  • Cell-Wall Remodeling by the Zinc-Protease AmpDh3 from Pseudomonas aeruginiosa Lee M, Artola-Recolons C, Carrasco-Lopez C, Martinez-Caballero S, Hesek D, Spink E, Lastochkin E, Zhang W, Hellman LM, Boggess B, Hermoso JA, Mobashery S, J Am Chem Soc., 2013, 135, 12604.
  • Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site Alves NJ, Champion MM, Stefanick JF, Handlogten MW, Moustakas DT, Shi Y, Shaw BF, Navari RM, Kiziltepe T, Bilgicer B, Biomaterial, 2013, 34, 5700.
  • Capillary zone electrophoresis-multiple reaction monitoring from 100 pg of RAW 264.7 cell lysate digest Sun L, Li Y, Champion MM, Zhu G, Wojcik R, Dovichi NJ, Analyst, 2013, 138, 3181.
  • Reactions of the Three AmpD Enzymes of Pseudomonas aeruginosa Zhang W, Lee M, Hesek D, Lastochkin E, Boggess B, Mobashery S, J Am Chem Soc 2013, 135, 4950.
  • Reactions of all Escherichia coli lytic transglycosylases with bacterial cell wall Lee M, Hesek D, Llarrull Ll, Lastochkin E, Pi H, Boggess B, Mobashery S, J Am Chem Soc., 2013, 135, 3311.
  • Quantitative Multiple Reaction Monitoring of Peptide Abundance Introduced via a Capillary Zone Electrophoresis-Electrospray Interface Li Y, Wojcik R, Dovichi NJ, Champion MM, Anal Chem, 2012 Jul 17; 84(14) pp 6116-21. Epub 2012 Jun 27. PubMed PMID: 22690842.
  • Inhibitors for Bacterial Cell-Wall Recycling Yamaguchi, T., Blaszquez, B., Hesek, D., Lee, M., Llarrull, L., Boggess, B., Oliver, A.G., Fisher, J.F., Mobashery, S. ACS Med Chem Lett, 2012, 3, 238.
  • On the Homogeneous Catalysis of Photochemical and Thermal O2-degrading of Lignin in Aqueous Solution. Mechanistic Observations on the Processes Catalyzed by lIII(phthalocyaninetetrasufonate)3- and CoIIIdimethylgloximate Complexes Ruiz, G.T., Juliarena, M.P., Ferraudi, G., Lappin, A.G., Boggess, W., Feliz, M.R. Polyhedron, 2012, 38, 36.
  • Cutting edge: Evidence for a dynamically driven T cell signaling mechanism Hawse WF, Champion MM, Joyce MV, Hellman LM, Hossain M, Ryan V, Pierce BG, Weng Z, Baker BM. J Immunol., 2012, Jun 15, 188(12) pp 5819-23. Epub 2012 May 18. PubMed PMID: 22611242; PubMed Central PMCID: PMC3375328.
  • Direct detection of bacterial protein secretion using whole colony proteomics Champion MM, Williams EA, Kennedy GM, Champion PA. Mol Cell Proteomics, 2012, May 10. [Epub ahead of print] PubMed PMID: 22580590.
  • Capillary zone electrophoresis-electrospray ionization-tandem mass spectrometry as an alternative proteomics platform to ultraperformance liquid chromatography-electrospray ionization-tandem mass spectrometry for samples of intermediate complexity Li Y, Champion MM, Sun L, Champion PA, Wojcik R, Dovichi NJ. Anal Chem., 2012, Feb 7;84(3) pp 1617-22. Epub 2012 Jan 9. PubMed PMID: 22182061; PubMed Central PMCID: PMC3277681.
  • Zwint-1 is a Novel Aurora B Substrate Required for the Assembly of a Dynein-binding Platform on Kinetochores James M. Kasuboski, Jason R. Bader, Patricia S. Vaughan, Sinji B.F. Tauhata, Michael Winding, Meghan M. Morrisey, Michelle V. Joyce, William Boggess, Larissa Vos, Gordon K. Chan, Edward H. Hinchcliffe, and Kevin T. Vaughan, Mol. Biol. Cell., 2011, 22 (18), pp 3318-3330.
  • Importance of Position 170 in the Inhibition of GES Type β-Lactamases by Clavulinic Acid Frase H, Toth M, Champion MM, GiaoAntunes N, Vakulenko S. Antimicrobial Agents and Chemotherapy 2011, 55 (4), pp 1556-1562.
  • Inhibition of the GES-2 β-Lactamase by Tazobactum: Detection of Reaction Intermediates by UV and Mass Spectrometry and X-Ray Crystallography Frase, H.; Smith, C.A.; Toth, M.; Champion, M.M.; Mobashery, S.; Vakulenko, S.B. JBC 2011, 286, pp 14396-14409. 
  • Novel Microbial Biodegradation and Metabolite Toxicity of Three Pyridinium-Cation Ionic Liquids Docherty, K.M.; Joyce, M.V.; Kulacki, K.J.; Kulpa, C.F. Green Chem. 2010; 12, pp 701-712. 
  • The Absorption Spectrum, Mass Spectrometric Properties and Electronic Structure of ortho-Benzoquinone Albarran, G.; Boggess, W.; Rassolov, V.; Schuler, R.H. J. Phys. Chem. A, 2010; 114 (28), pp 7470–7478.
  • Synthesis, Kinetic Characterization and Metabolism of Diastereomeric 2-(1-(4-Phenoxyphenyl-sulfonyl) ethyl)thiiranes as Potent Gelatinase and MT1-MMP Inhibitors Gooyit,M.; Lee, M.; Hesek, D; Boggess, B; Oliver, A.G.; Fridman, R.; Mobashery, S.; Chang, M.Chem. Biol. Drug Des. 2009; 74 (6), pp 535-546.
  • Probing Interactions between CLIP-170, EB1, and Microtubules Gupta, K.K.; Joyce, M.V.; Slabbekoorn, A.R.; Zhu, Z.; Paulson, B.A.; Boggess, B.; Goodson, H.V. J. Mol. Biol. 2009; 395 (5), pp 1049-1062.
  • Bacterial AmpD at the Crossroads of Peptidoglycan Recycling and Manifestation of Antibiotic Resistance Lee, M.; Zhang, W.; Hesek, D.; Noll, B. C.; Boggess, B.; Mobashery, S.J. Am. Chem. Soc. 2009,131, pp 8742-8743.
  • A Potent Gelatinase Inhibitor with Anti-Tumor-Invasive Activity and its Metabolic Disposition Lee, M.; Celenza, G.; Boggess, B.; Blasé, J.; Shi, Q.; Toth, M.; Bernardo, M.M.; Wolter, W.R.; Suckow, M.A.; Hesek, D.; Noll, B.C.; Fridman, R.; Mobashery, S.; Chang, M. Chem. Biol. Drug Des. 2009; 73 (2); pp 189-202.
  • Mycobacterium avium glycopeptidolipids require specific acetylation and methylation patterns for signaling through TLR2 Sweet, L.; Zhang, W.; Torres-Fewell, H.; Serianni, A.; Boggess, W.; Schorey, J. J. Biol. Chem.; 2008; 283 (48); pp 33221-33231.
  • Lytic Transglycosylase MltB of Escherichia coli and Its Role in Recycling of Peptidoglycan Strands of Bacterial Cell Wall Suvorov, M.; Lee, M.; Hesek, D.; Boggess, B.; Mobashery, S. J. Am. Chem. Soc. 2008, 130, 11878.
  • Fast Selective Detection of Polar Brominated Disinfection Byproducts in Drinking Water Using Precursor Ion Scans Zhang, X.; Talley, J. W.; Boggess, B.; Ding, G.; Birdsell, D. Environ. Sci. Technol. 2008; 42 (17); 6598.
  • Metabolism of (4-Phenoxyphenylsulfonyl)methylthiirane, a Selective Gelatinase Inhibitor Celenza, G.; Villegas-Estrada, A.; Lee, M.; Boggess, B.; Forbes, C.; Wolter, W. R.; Suckow, A.; Mobashery, S.; Chang, M. Chem. Biol. Drug Des. 2008, 71, 187.
  • Metabolism of a Highly Selective Gelatinase Inhibitor Generates Active Metabolite Lee, M.; Villegas-Estrada, A.; Celenza, G.; Boggess, B.; Toth, M.; Kreitinger, G.; Forbes, C.; Fridman, R.; Mobashery, S.; Chang, M., Chem. Biol. Drug Des. 2007, 70, 371.
  • Assembly of a homochiral, body-centered cubic network composed of vertex-shared Mg12 cages: use of electrospray ionization mass spectrometry to monitor metal carboxylate nucleation Rood, J. A.; Boggess, W. C.; Noll, B. C.; Henderson, K. W., J. Am. Chem. Soc., 2007; 129, 13675.
  • Open-tubular Capillary Electrochromatography - Mass Spectrometry with Sheathless Nanoflow Electrospray Ionization for Analysis of Amino Acids and Peptides Chang, C.; Boggess, B.; Chen, Z., J. Mass Spectrometry, 2007, 42, 244.
  • The role of Drosophila ninaG oxidoreductase in visual pigment chromophore biogenesis Ahmad, S.T.; Joyce, M.V.; Boggess, B.; O'Tousa J.E.J Biol Chem. 2006, 281, 9205.
  • The Drosophila ninaG oxidoreductase acts in visual pigment chromophore production Sarfare, S.; Ahmad, S.T.; Joyce, M.V.; Boggess, B.; O'Tousa J.E. J Biol Chem. 2005 Mar 25; 280, 11895.
  • Facile Pd-Catalyzed Cross-coupling of 2’-Deoxyguanosine O6-Arylsulfonates with Arylboronic Acids Lakshman, M.K.; Thomson, P.F.; Nuqui, M.A.; Hilmer, J.H.; Sevova, N.; Boggess, B., Org. Lett. 2002, 4, 1479.