Weaver, S. D.; Hu, D. D.; Jones, B. S.; Champion, P. A.; Champion, M. M. PDIM/PGL-deficient Mycobacterium marinum shows disrupted protein secretion measured with bottom-up label-free quantitative analysis in data-dependent acquisition mode on a timsTOF Pro 2 mass spectrometer. Microbiol. Resour. Announc.2026, 15, (2), e01161-25.
Collars, O. A.; Weaver, S. D.; Hernandez, R. L.; Champion, M. M.; Champion, P. A. Tyloxapol inhibits ESX-1 secretion in Mycobacterium marinum. J. Bacteriol.2026, 208, (5), e00136-26.
Collars, O. A.; Hernandez, R. L.; Weaver, S. D.; Prest, R. J.; Manu, C.; Viswanathan, G.; Cronin, R. M.; Jones, B. S.; Tobin, D. M.; Champion, M. M. pH-responsive substrate switching in mycobacterial type VII ESX secretion. Msphere2026, 11, (5), e00056-26.
A. Chandran; N. L. Dominique; G. Kaur; L. C. Ekowo; V. Clark; P. Nalaoh; I. M. Jensen; M. D. Aloisio; C. M. Crudden; N. Arroyo-Currás; D. M. Jenkins; J. P. Camden, Forming N-heterocyclic carbene monolayers: Not all deposition methods are the same. Nanoscale 2025, 17, (9), 5413.
Reynolds, T. S.; Hu, D. D.; Weaver, S. D.; Ronck, E. C.; Mishra, S. J.; Champion, M. M.; Blagg, B. S. J. Proteomic analysis of Hsp90β-selective inhibitors against triple-negative breast cancer to gain a mechanistic insight. Mol. Cell. Proteomics2025, 24, (9).
N. L. Dominique; P. Nalaoh; D. M. Jenkins; R. Vaia; K. Park; J. P. Camden, One-step functionalization of gold nanorods with N-heterocyclic carbene ligands. RSC Adv. 2025, 15, (7), 5007.
C. M. Kerr; O. L. Schneider; S. Tichy; B. J. Huge; M. M. Champion, Capillary isoelectric focusing of proteins and peptides using an in-line CIEF-ESI interface with improved MS characteristics. Analytical Chemistry 2025, 97, (1), 649.
C. Kim; R. Molina; M. Lee; A. Garay-Alvarez; J. Yang; Y. Qian; B. T. Birhanu; D. Hesek; J. A. Hermoso; M. Chang; S. Mobashery, Reactions of SleC, its structure and inhibition in mitigation of spore germination in Clostridioides difficile. J. Am. Chem. Soc. 2025, 147, (6), 5060.
D. Prado; R. Cattley; A. Sonego; P. Sutariya; S. Wu; M. Lee; W. Boggess; M. Shlomchik; W. Hawse, The phospholipid kinase PIKFYVE is essential for Th17 differentiation. J. Exp. Med. 2025,222, (2): e20240625.
V. T. Nguyen; B. T. Birhanu; V. Miguel-Ruano; C. Kim; M. Batuecas; J. Yang; A. M. El-Araby; E. Jimenez-Faraco; V. A. Schroeder; A. Alba; N. Rana; S. Sader; C. A. Thomas; R. Feltzer; M. Lee; J. F. Fisher; J. A. Hermoso; M. Chang; S. Mobashery, Restoring susceptibility to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus. Nat. Chem. Biol. 2025, 21, 482.
Z. M. Zhang; H. S. Sanders; V. Dragun; S. Cole; B. D. Smith, Fluorescent molecular probe for imaging hypoxia in 2D cell culture monolayers and 3istribution in a spheroid. ACS Appl. Mater. Inter. 2025, 17, (12), 18046.
Wang, C.W.; Weaver, S. D.; Boonpattrawong, N.; Schuster-Little, N.; Patankar, M.; Whelan, R. J. A revised molecular model of ovarian cancer biomarker CA125 (MUC16) enabled by long-read sequencing. Cancer Res. Commun.2024, 4, (1), 253–263.
C. Abou-Khalil; L. Chernysheva; A. Miller; A. Abarca-Perez; G. Peaslee; P. Herckes; P. Westerhoff; K. Doudrick, Enhancing the thermal mineralization of perfluorooctanesulfonate on granular activated carbon using alkali and alkaline-earth metal additives. Environ. Sci. Technol. 2024, 58, (25), 11162.
L. F. Avila-Cobian; S. De Benedetti; H. Hoshino; V. Nguyen; A. M. El-Araby; S. Sader; D. D. Hu; S. L. Cole; C. Kim; J. F. Fisher; M. M. Champion; S. Mobashery, Lytic transglycosylase slt of pseudomonas aeruginosa as a periplasmic hub protein. Protein Sci. 2024, 33, (7), e5038.
W. K. Cao; P. Y. Chu; M. L. Bruening; R. L. Shi; H. Hernandez-Barry; J. C. Tran, Efficient, low-cost, and high-throughput sodium dodecyl sulfate (SDS) removal from protein digests using weak-anion exchange. J. Am. Soc. Mass Spectrom. 2024, 36, (4), 680.
V. Charlestin; E. Tan; C. E. Arias-Matus; J. Wu; M. C. Miranda-Vergara; M. Lee; M. Wang; D. T. Nannapaneni; P. Tennakoon; B. S. J. Blagg; B. L. Ashfeld; W. Kaliney; J. Li; L. E. Littlepage, Evaluation of the mammalian aquaporin inhibitors auphen and z433927330 in treating breast cancer. Cancers 2024, 16, (15), 2714.
G. R. Lee; D. B. Go; C. P. O'Brien, Nonthermal plasma-stimulated C-N coupling from CH4 and N2 depends on the presence of surface CH x and plasma-phase CN species. ACS Appl. Mater. Inter. 2024, 16, (22), 28367.
T. J. Lundgren; P. L. Clark; M. M. Champion, Fit for purpose approach to evaluate detection of amino acid substitutions in shotgun proteomics. J. Proteome Res. 2024, 23, (4), 1263.
V. Miguel-Ruano; I. Acebrón; M. Lee; A. J. Martín-Galiano; C. Freton; U. P. de José; B. Ramachandran; F. Gago; M. Kjos; D. Hesek; C. Grangeasse; L. S. Håvarstein; D. Straume; S. Mobashery; J. A. Hermoso, Characterization of VldE (spr1875), a Ppneumococcal two-state l,d-endopeptidase with a four-zinc cluster in the active site. ACS Catal. 2024, 14, (24), 18786.
J. J. Morsby; Z. M. Zhang; A. Burchett; M. Datta; B. D. Smith, Ratiometric near-infrared fluorescent probe for nitroreductase activity enables 3d imaging of hypoxic cells within intact tumor spheroids. Chem. Sci. 2024, 15, (10), 3633.
C. B. Mousseau; D. D. Hu; S. R. Schultz; M. M. Champion, Quenching trypsin is unnecessary in filter-based bottom-up proteomics. J. Am. Soc. Mass Spectrom. 2024, 35, (8), 2028.
R. O'Connell; N. J. Dolphin; G. Ferraudi; M. Lee; C. V. Stauffacher; P. Helquist; O. Wiest, Synthesis of Caged HMG-CoA reductase substrates for elucidation of cellular pathways. J. Org. Chem. 2024,89, 18739.
J. Olesk; D. Donahue; J. Ross; C. Sheehan; Z. Bennett; K. Armknecht; C. Kudary; J. Hopf; V. A. Ploplis; F. J. Castellino; S. W. Lee; P. D. Nallathamby, Antimicrobial peptide-conjugated phage-mimicking nanoparticles exhibit potent bactericidal action against streptococcus pyogenes in murine wound infection models. Nanoscale Advances 2024, 6, (4), 1145.
K. R. Olson; K. J. Clear; T. Takata; Y. Gao; Z. L. Ma; E. Pfaff; A. Travlos; J. Luu; K. Wilson; Z. Joseph; I. Kyle; S. M. Kasko; P. J. Jones; J. Fukuto; M. Xian; G. Wu; K. D. Straub, Reaction mechanisms of h2s oxidation by naphthoquinones. Antioxidants-Basel 2024, 13, (5), DOI10.3390/antiox13050619.
K. R. Olson; T. Takata; K. J. Clear; Y. Gao; Z. L. Ma; E. Pfaff; K. Mouli; T. A. Kent; P. Jones; J. Fukuto; G. Wu; K. D. Straub, The sod1 inhibitor, lcs-1, oxidizes h2s to reactive sulfur species, directly and indirectly, through conversion of sod1 to an oxidase. Antioxidants-Basel 2024, 13, (8), DOI10.3390/antiox13080991.
D. L. Poirier; D. Hale; P. M. Barboun; J. C. Hicks, Toward sustainable production of n-containing products via nonthermal plasma-enhanced conversion of natural gas resources. J. Environ. Chem. Eng. 2024, 12, (2), 111970.
W. T. M. Seo; M. N. Riffel; A. G. Oliver; E. Y. Tsui, Metal-cation-induced shifts in thiolate redox and reduced sulfur speciation. Chem. Sci. 2024, 15, (19), 7332.
W. T. M. Seo; V. A. Tsang; M. Ballesteros, II; E. Y. Tsui, Ligand basicity and chelate effects on sulfur insertion vs. Sulfur reduction by zinc thiolate complexes. Chem-Eur. J. 2024, 30, (41), DOI10.1002/chem.202401280.
M. Toth; N. K. Stewart; A. O. Maggiolo; P. J. Quan; M. M. K. Khan; J. D. Buynak; C. A. Smith; S. B. Vakulenko, Decarboxylation of the catalytic lysine residue by the c5α-methyl-substituted carbapenem NA-1-157 leads to potent inhibition of the OXA-58 carbapenemase. ACS Infect. Dis. 2024, 10, (12), 4347.
J. Y. Yang; R. Ostafe; M. L. Bruening, In-membrane enrichment and peptic digestion to facilitate analysis of monoclonal antibody glycosylation. Anal. Chem. 2024, 96, (16), 6347.
Q. Yu; J. B. Fein, Analysis of total thiol concentrations in environmental samples using ultra-high performance liquid chromatography-mass spectrometry (UHPLC-MS). Chem. Geol. 2024, 644, 121837.
Weaver, S. D.; DeRosa, C. M.; Schultz, S. R.; Champion, M. M. PrIntMap-R: An online application for intraprotein intensity and peptide visualization from bottom-up proteomics. J. Proteome Res.2023, 22, (2), 432–441.
L. F. Avila-Cobian; H. Hoshino; M. E. Horsman; V. T. Nguyen; Y. Y. Qian; R. Feltzer; C. Kim; D. D. Hu; M. M. Champion; J. F. Fisher; S. Mobashery, Amber-codon suppression for spatial localization and in vivo photoaffinity capture of the interactome of the pseudomonas aeruginosa rare lipoprotein a lytic transglycosylase. Protein Sci. 2023, 32, (10), e4781.
K. Breger; J. Brown, Elucidating the kinetic mechanism of human Mettl16. Biochemistry 2023, 62, 494.
W. K. Cao; M. L. Bruening, Analysis of protein glycosylation after rapid digestion using protease-containing membranes in spin columns. J. Am. Soc. Mass Spectrom. 2023, 34, (6), 1086.
O. A. Collars; B. S. Jones; D. D. Hu; S. D. Weaver; T. A. Sherman; M. M. Champion; P. A. Champion, An N-acetyltransferase required for esat-6 n-terminal acetylation and virulence in mycobacterium marinum. Mbio 2023, 14, (5).
C. M. DeRosa; S. D. Weaver; C. W. Wang; N. Schuster-Little; R. J. Whelan, Simultaneous n-deglycosylation and digestion of complex samples on s-traps enables efficient glycosite hypothesis generation. ACS Omega 2023, DOI10.1021/acsomega.2c08071.
N. L. Dominique; I. M. Jensen; G. Kaur; C. Q. Kotseos; W. C. Boggess; D. M. Jenkins; J. P. Camden, Giving gold wings: Ultrabright and fragmentation free mass spectrometry reporters for barcoding, bioconjugation monitoring, and data storage. Angew. Chem., Int. Ed. Engl. 2023, 62, (21), DOI10.1002/anie.202219182.
C. Kim; M. Lee; B. T. Birhanu; D. Hesek; M. Chang; S. Mobashery, Synthesis of muramyl-d-lactam in spore peptidoglycan of clostridioides difficile. ChemBioChem 2023, 24, (11), e202300282.
C. Kim; S. Tomoshige; M. Lee; H. I. Zgurskaya; S. Mobashery, Penetration through outer membrane and efflux potential in Pseudomonas aeruginosa of bulgecin a as an adjuvant to b-lactam antibiotics. Antibiotics-Basel 2023, 12, (2), 358.
S. Martinez-Caballero; C. Freton; R. Molina; S. G. Bartual; V. Gueguen-Chaignon; C. Mercy; F. Gago; K. V. Mahasenan; I. G. Munoz; M. Lee; D. Hesek; S. Mobashery; J. A. Hermoso; C. Grangeasse, Molecular basis of the final step of cell division in Streptococcus pneumoniae. Cell Rep. 2023, 42, (7), 112756.
K. Olson; K. Clear; Y. Gao; Z. Ma; N. Cieplik; A. Fiume; D. Gaziano; S. Kasko; J. Luu; E. Pfaff; A. Travlos; C. Velander; K. Wilson; E. Edwards; K. Straub; G. Wu, Redox and nucleophilic reactions of naphthoquinones with small thiols and their effects on oxidization of hs to inorganic and organic hydropolysulfides and thiosulfate. Int. J. Mol. Sci. 2023, 24, (8), 7516.
K. A. Ryan; M. L. Bruening, Online protein digestion in membranes between capillary electrophoresis and mass spectrometry. Analyst 2023, 148, (7), 1611.
J. Shin; B. Kim; T. W. Lager; F. Mejia; I. Guldner; C. Conner; S. Y. Zhang; A. D. Panopoulos; B. Bilgicer, A nanotherapeutic approach to selectively eliminate metastatic breast cancer cells by targeting cell surface grp78. Nanoscale 2023, 15, (32), 13322.
F. R. Sterling; J. D'Amico; A. M. Brumfield; K. L. Huegel; P. S. Vaughan; K. Morris; S. Schwarz; M. Joyce; B. Boggess; M. M. Champion; K. Maciuba; P. Allen; E. Marasco; G. Koch; P. Gonzalez; S. Hodges; S. Leahy; E. Gerstbauer; E. H. Hinchcliffe; K. T. Vaughan, Stard9 is a novel lysosomal kinesin required for membrane tubulation, cholesterol transport and purkinje cell survival. J. Cell Sci. 2023, 136, (5), jcs260662.
C. W. Wang; E. K. Hanson; L. Minkoff; R. J. Whelan, Individual recombinant repeats of muc16 display variable binding to ca125 antibodies. Cancer Biomark. 2023, 37, (2), 85.
H. D. Whitehead; K. L. Hayes; J. A. Swartz; M. Lieberman, Development and validation of a liquid chromatography tandem mass spectrometry method for the analysis of 53 benzodiazepines in illicit drug samples. Forensic Chem. 2023, 35, 100512.
H. D. Whitehead; K. L. Hayes; J. A. Swartz; E. Prete; L. Robison-Taylor; M. E. Mackesy-Amiti; A. D. Jimenez; M. Lieberman, Validated method for the analysis of 22 illicit drugs and their metabolites via liquid chromatography tandem mass spectrometry (LC-MS/MS) in illicit drug samples collected in chicago, il. Forensic Chem. 2023, 33, 100475.
Weaver, S. D.; Schuster-Little, N.; Whelan, R. J. Preparative capillary electrophoresis (CE) fractionation of protein digests improves protein and peptide identification in bottom-up proteomics. Anal. Methods2022, 14, (11), 1103–1110.